SCHEDULE.
REGISTRATION
09:00-09:25 AM Registration opens / coffee and tea served
SESSION 1
09:25-09:30 AM Opening address
09:30-10:15 AM Professor Elizabeth Hartland (Doherty Institute for Infection and Immunity)
"No time to die: pathogen-driven host cell survival"
INVITED
10:15-10:35 AM Georgia Atkin-Smith (La Trobe Institute for Molecular Science)
"Are apoptotic bodies the Trojan horse for Influenza A Virus pathogenesis?"
10:35-10:55 AM Marcel Doerflinger (The Walter and Eliza Hall Institute of Medical Research)
"Utilizing in vitro CRISPR/Cas9 screening platforms for functional genomics to decipher host cell death mechanisms in chronic and acute infectious diseases"
10:55-11:15 AM Cristina Giogha (Doherty Institute for Infection and Immunity)
"The type III effector NleB from enteropathogenic E. coli antagonises death receptor signalling"
MORNING TEA AND POSTER PREVIEW
11:15-11:45 AM Morning tea served / Poster preview
SESSION 2
11:45-12:05 PM Kate McArthur (The Walter and Eliza Hall Institute of Medical Research)
"Caspases suppress DAMP signaling triggered by apoptotic mitochondria"
12:05-12:25 PM Matthew Eramo (Monash University)
"Autophagy is essential for maintenance of skeletal muscle structure and function"
12:25-12:45 PM Jonathan Bernardini (The Walter and Eliza Hall Institute of Medical Research)
"Parkin-mediated ubiquitination of the pro-apoptotic protein Bak"
12:25-01:15 PM 3 min rapid fire presenters
Holly Anderton (The Walter and Eliza Hall Institute of Medical Research)
"Inhibitor of APoptosis proteins (IAPs) limit inflammation in the skin"
Paul Baker (The Walter and Eliza Hall Institute of Medical Research)
"Phosphorylation of the pyrin inflammasome regulates pyroptosis and IL-1b release"
Amy Baxter (La Trobe Institute for Molecular Science)
"Phosphatidylinositol-4,5 bisphosphate (PIP2)-mediated membrane permeabilisation is a
conserved mechanism of cytolysis amongst solanaceous anti-cancer plant defensins"
Tirta Djajawi (The Walter and Eliza Hall Institute of Medical Research)
"Mitochondrial E3 ligase March5 controls Mcl-1 stability through Noxa binding"
Reema Jain (The Walter and Eliza Hall Institute of Medical Research)
"A critical epithelial survival axis regulated by epidermal growth factor and MCL-1 maintains thymic function"
Weidong Jing (Australian National University)
"Two distinct mechanisms of phospholipid flippase inactivation in mouse platelet apoptosis and activation"
Christina Nedeva (La Trobe Institute for Molecular Science)
"Role of FUMR in sepsis-induced lymphopenia"
Jaclyn Pearson (Doherty Institute for Infection and Immunity)
"Necroptosis inhibition by pathogenic E. coli"
Che Stafford (The Walter and Eliza Hall Institute of Medical Research)
"A mystery resolved: IAPs in NOD signalling"
Rachel Uren (The Walter and Eliza Hall Institute of Medical Research)
"Disordered clusters of Bak dimers rupture mitochondria during apoptosis"
LUNCH AND POSTER SESSION
LUNCH AND POSTER SESSION
01:15-02:15 PM Lunch served / Poster session
01:15-02:15 PM Lunch served / Poster session
SESSION 3
02:15-02:35 PM Maria Tanzer (The Walter and Eliza Hall Institute of Medical Research)
"cIAP antagonists and IFNg activate novel caspase-10 and RIPK1 dependent cell death pathways"
02:35-02:55 PM Janson Tse (Olivia Newton-John Cancer Research Institute)
"ATF3-mediated repression of BCL-XL is a critical determinant of HDAC-inhibitor induced
apoptosis across tumour types"
02:55-03:15 PM Gregor Ebert (The Walter and Eliza Hall Institute of Medical Research)
"Birinapant, a potent smac mimetic, antagonises cellular inhibitors of apoptosis and promotes clearance of overwhelming infections in vivo"
INVITED
03:15-04:00 PM Professor Suzanne Cory (The Walter and Eliza Hall Institute of Medical Research)
"Bcl-2 and the Long March to BH3 Mimetics"
AWARDS, CLOSING REMARKS AND MIXER
04:00-04:10 PM Awards presentation and closing remarks
04:10 onwards Afternoon tea / Drinks / Pizza