SCHEDULE.
REGISTRATION
09:00-09:25 AM Registration opens / coffee and tea served
SESSION 1
09:25-09:30 AM Opening address
09:30-10:15 AM Professor Elizabeth Hartland (Doherty Institute for Infection and Immunity)
"No time to die: pathogen-driven host cell survival"
INVITED
10:15-10:35 AM Georgia Atkin-Smith (La Trobe Institute for Molecular Science)
"Are apoptotic bodies the Trojan horse for Influenza A Virus pathogenesis?"
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10:35-10:55 AM Marcel Doerflinger (The Walter and Eliza Hall Institute of Medical Research)
"Utilizing in vitro CRISPR/Cas9 screening platforms for functional genomics to decipher host cell death mechanisms in chronic and acute infectious diseases"
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10:55-11:15 AM Cristina Giogha (Doherty Institute for Infection and Immunity)
"The type III effector NleB from enteropathogenic E. coli antagonises death receptor signalling"
MORNING TEA AND POSTER PREVIEW
11:15-11:45 AM Morning tea served / Poster preview
SESSION 2
11:45-12:05 PM Kate McArthur (The Walter and Eliza Hall Institute of Medical Research)
"Caspases suppress DAMP signaling triggered by apoptotic mitochondria"
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12:05-12:25 PM Matthew Eramo (Monash University)
"Autophagy is essential for maintenance of skeletal muscle structure and function"
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12:25-12:45 PM Jonathan Bernardini (The Walter and Eliza Hall Institute of Medical Research)
"Parkin-mediated ubiquitination of the pro-apoptotic protein Bak"
12:25-01:15 PM 3 min rapid fire presenters
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Holly Anderton (The Walter and Eliza Hall Institute of Medical Research)
"Inhibitor of APoptosis proteins (IAPs) limit inflammation in the skin"
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Paul Baker (The Walter and Eliza Hall Institute of Medical Research)
"Phosphorylation of the pyrin inflammasome regulates pyroptosis and IL-1b release"
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Amy Baxter (La Trobe Institute for Molecular Science)
"Phosphatidylinositol-4,5 bisphosphate (PIP2)-mediated membrane permeabilisation is a
conserved mechanism of cytolysis amongst solanaceous anti-cancer plant defensins"
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Tirta Djajawi (The Walter and Eliza Hall Institute of Medical Research)
"Mitochondrial E3 ligase March5 controls Mcl-1 stability through Noxa binding"
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Reema Jain (The Walter and Eliza Hall Institute of Medical Research)
"A critical epithelial survival axis regulated by epidermal growth factor and MCL-1 maintains thymic function"
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Weidong Jing (Australian National University)
"Two distinct mechanisms of phospholipid flippase inactivation in mouse platelet apoptosis and activation"
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Christina Nedeva (La Trobe Institute for Molecular Science)
"Role of FUMR in sepsis-induced lymphopenia"
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Jaclyn Pearson (Doherty Institute for Infection and Immunity)
"Necroptosis inhibition by pathogenic E. coli"
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Che Stafford (The Walter and Eliza Hall Institute of Medical Research)
"A mystery resolved: IAPs in NOD signalling"
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Rachel Uren (The Walter and Eliza Hall Institute of Medical Research)
"Disordered clusters of Bak dimers rupture mitochondria during apoptosis"
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LUNCH AND POSTER SESSION
LUNCH AND POSTER SESSION
01:15-02:15 PM Lunch served / Poster session
01:15-02:15 PM Lunch served / Poster session
SESSION 3
02:15-02:35 PM Maria Tanzer (The Walter and Eliza Hall Institute of Medical Research)
"cIAP antagonists and IFNg activate novel caspase-10 and RIPK1 dependent cell death pathways"
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02:35-02:55 PM Janson Tse (Olivia Newton-John Cancer Research Institute)
"ATF3-mediated repression of BCL-XL is a critical determinant of HDAC-inhibitor induced
apoptosis across tumour types"
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02:55-03:15 PM Gregor Ebert (The Walter and Eliza Hall Institute of Medical Research)
"Birinapant, a potent smac mimetic, antagonises cellular inhibitors of apoptosis and promotes clearance of overwhelming infections in vivo"
INVITED
03:15-04:00 PM Professor Suzanne Cory (The Walter and Eliza Hall Institute of Medical Research)
"Bcl-2 and the Long March to BH3 Mimetics"
AWARDS, CLOSING REMARKS AND MIXER
04:00-04:10 PM Awards presentation and closing remarks
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04:10 onwards Afternoon tea / Drinks / Pizza